About dbCRID

  • dbCRID (Database of Chromosomal Rearrangements In Diseases) is the largest database of curated database of human Chromosome rearrangements and associated diseases.
  • Current release: v 0.9 (06/30/2010).
  • Please direct questions and comments to dbCRID@biolead.org.
  • Related Databases

  • AtlasGeneticsOncology, Atlas of Genetics and Cytogenetics in Oncology and Haematology
  • ChimerDB 2.0, A knowledgebase for fusion genes updated
  • CytoD 1.0, A database of cytogenetic abnormalities.
  • DACRO, A disease-Associated Chromosomal Rearrangements Online.
  • Decipher, , A Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources
  • HYBRIDdb,A database of hybrid genes in the human genome.
  • Mitelman, A database of Chromosome Aberrations and Gene Fusions in Cancer.
  • SKY/M-FISH &CGH, A public platform for investigators to share and compare their molecular cytogenetic data.
  • TICdb, A database of Translocation breakpoints In Cancer.
  • References

  • Kong F, Zhu J, Wu J, Peng J, Wang Y, Wang Q, Fu S, Yuan L and Li T: dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. [PubMed] [Full-text]
  • Event ID: 11262 ( Case ID: 11979 )
    Disease: T-Cell Acute Promyelocytic Leukemia ( DOID: 8552 ) All events related to this disease.
    Event Information
    Precision: B
    Chromosome Rearrangement Type: Reciprocal Translocation
    Chromosome: 15, 17
    Karyotype: t(15;17)(q22;q21)
    Breakpoints Information:
    First Breakpoint:
    Location: q22
    This breakpoint occurs in intron3 of NM_033238.2.
    Second Breakpoint:
    Location: q21
    This breakpoint occurs in intron2 of NM_001024809.2.
    Junction Sequence is Unavailable.
    Experimental Method: PCR
    Reference Information
    PubMed ID: 18650449
    Authors: Hasan SK,Mays AN,Ottone T,Ledda A,La Nasa G,Cattaneo C,Borlenghi E,Melillo L,Montefusco E,Cervera J,Stephen C,Satchi G,Lennard A,Libura M,Byl JA,Osheroff N,Amadori S,Felix CA,Voso MT,Sperr WR,Esteve J,Sanz MA,Grimwade D,Lo-Coco F
    Journal: Blood
    Go to Genome Browser ( Click the image )