About dbCRID

  • dbCRID (Database of Chromosomal Rearrangements In Diseases) is the largest database of curated database of human Chromosome rearrangements and associated diseases.
  • Current release: v 0.9 (06/30/2010).
  • Please direct questions and comments to dbCRID@biolead.org.
  • Related Databases

  • AtlasGeneticsOncology, Atlas of Genetics and Cytogenetics in Oncology and Haematology
  • ChimerDB 2.0, A knowledgebase for fusion genes updated
  • CytoD 1.0, A database of cytogenetic abnormalities.
  • DACRO, A disease-Associated Chromosomal Rearrangements Online.
  • Decipher, , A Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources
  • HYBRIDdb,A database of hybrid genes in the human genome.
  • Mitelman, A database of Chromosome Aberrations and Gene Fusions in Cancer.
  • SKY/M-FISH &CGH, A public platform for investigators to share and compare their molecular cytogenetic data.
  • TICdb, A database of Translocation breakpoints In Cancer.
  • References

  • Kong F, Zhu J, Wu J, Peng J, Wang Y, Wang Q, Fu S, Yuan L and Li T: dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. [PubMed] [Full-text]
  • Event ID: 10649 ( Case ID: 10985 )
    Disease: Extraskeletal Myxoid Chondrosarcomas ( DOID: 2694 )
    Event Information
    Precision: A
    Chromosome Rearrangement Type: Reciprocal Translocation
    Chromosome: 9, 15
    Karyotype: t(9;15)(q22.33;q21.3)
    Breakpoints Information:
    First Breakpoint:
    Location: q22.33
    Exact position: Chr9: 102590323bp
    This breakpoint occurs in extron3 of NM_173200.1.
    Second Breakpoint:
    Location: q21.3
    Exact position: Chr15: 57384089bp
    This breakpoint occurs in extron4 of NM_207040.1.
    Junction Sequence(5'):
    CTGTTTCCCAGATTAGAGAACAGTGAACCCAATGCTGCCTGTTGGCTAGAAAACAAGTGTTAACTTGCTTCTGAGAGACCCTTTTCTCTGTCCCTGCAGAGGTAAGTTGGTAATTCTCTGCAAGTAGTCTTCTCAAAGCTTCTTTGGTCAGAGACATTTTTTATCCCTTTGTCCAGGAGGGACAGGTAAGTATCTAGAAG
    Junction Sequence(3'):
    TTTACAGACAGCCCTCATTACAGTGATCACTTGAATGACAGTCGATTAGGAGCCCATGAAGGCTTGTCCCCAACACCTTTCATGAACTCAAATCTGATGGATATGCCCTGCGTCCAAGCCCAATATAGCCCTTCCCCTCCAGGTTCCAGTTATGCGGCGCAGACATACAGCTCGGAATACACCACGGAGATCATGAACCC
    The Junction Sequence is Inferred.
    Note: Green and Blue color indicate 5' and 3' sequence according to the breakpoint.
    Experimental Method: FISH, PCR, DNA sequencing
    Reference Information
    PubMed ID: 11156374
    Authors: Sjögren H,Wedell B,Meis-Kindblom JM,Kindblom LG,Stenman G,Kindblom JM
    Journal: Cancer research
    Go to Genome Browser ( Click the image )