About dbCRID

  • dbCRID (Database of Chromosomal Rearrangements In Diseases) is the largest database of curated database of human Chromosome rearrangements and associated diseases.
  • Current release: v 0.9 (06/30/2010).
  • Please direct questions and comments to dbCRID@biolead.org.
  • Related Databases

  • AtlasGeneticsOncology, Atlas of Genetics and Cytogenetics in Oncology and Haematology
  • ChimerDB 2.0, A knowledgebase for fusion genes updated
  • CytoD 1.0, A database of cytogenetic abnormalities.
  • DACRO, A disease-Associated Chromosomal Rearrangements Online.
  • Decipher, , A Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources
  • HYBRIDdb,A database of hybrid genes in the human genome.
  • Mitelman, A database of Chromosome Aberrations and Gene Fusions in Cancer.
  • SKY/M-FISH &CGH, A public platform for investigators to share and compare their molecular cytogenetic data.
  • TICdb, A database of Translocation breakpoints In Cancer.
  • References

  • Kong F, Zhu J, Wu J, Peng J, Wang Y, Wang Q, Fu S, Yuan L and Li T: dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. [PubMed] [Full-text]
  • Event ID: 10387 ( Case ID: 12976 )
    Event Information
    Precision: A
    Chromosome Rearrangement Type: Duplication
    Chromosome: X
    Karyotype: dup(X)(q28;q28q28)
    Breakpoints Information:
    Insertion Breakpoint:
    Location: q28
    Exact position: ChrX: 153680107bp
    This breakpoint occurs in an intergenic region
    First Breakpoint:
    Location: q28
    Exact position: ChrX: 152863739bp
    This breakpoint occurs in intron4 of NM_001130997.1.
    Second Breakpoint:
    Location: q28
    Exact position: ChrX: 153680107bp
    This breakpoint occurs in an intergenic region
    Length of Duplication Segment is 816Kb.
    Junction Sequence(5'):
    TTTTTTGAGACTGGGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAGTGGTGCAATCTCAGCTCGCTGCAGCCCCCACCTCCTGGGCTCAAGTGATCCTCCCTGGCACACACCTGTAATTCCAGCTACTCGGAAGCGTGAGGAAGGATAATTGCTTTAGTCCGGGAGACGGAGGTTGCAGTGAGCCGAGATCACGCCACTGC
    Junction Sequence(3'):
    TTTTTTGAGACTGGGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAGTGGTGCAATCTCAGCTCGCTGCAGCCCCCACCTCCTGGGCTCAAGTGATCCTCCCCGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGTGTGCACCACAATGCCCAGCTATTTTTATTTTTATGTACATGAAAATTGGAACAGAATTAAAAAAAA
    The Junction Sequence is Inferred.
    Note: Green and Blue color indicate 5' and 3' sequence according to the breakpoint.
    Experimental Method: FISH, PCR, DNA sequencing
    Reference Information
    PubMed ID: 18385275
    Authors: Bauters M,Van Esch H,Friez MJ,Boespflug-Tanguy O,Zenker M,Vianna-Morgante AM,Rosenberg C,Ignatius J,Raynaud M,Hollanders K,Govaerts K,Vandenreijt K,Niel F,Blanc P,Stevenson RE,Fryns JP,Marynen P,Schwartz CE,Froyen G
    Journal: Genome research
    Go to Genome Browser ( Click the image )