About dbCRID

  • dbCRID (Database of Chromosomal Rearrangements In Diseases) is the largest database of curated database of human Chromosome rearrangements and associated diseases.
  • Current release: v 0.9 (06/30/2010).
  • Please direct questions and comments to dbCRID@biolead.org.
  • Related Databases

  • AtlasGeneticsOncology, Atlas of Genetics and Cytogenetics in Oncology and Haematology
  • ChimerDB 2.0, A knowledgebase for fusion genes updated
  • CytoD 1.0, A database of cytogenetic abnormalities.
  • DACRO, A disease-Associated Chromosomal Rearrangements Online.
  • Decipher, , A Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources
  • HYBRIDdb,A database of hybrid genes in the human genome.
  • Mitelman, A database of Chromosome Aberrations and Gene Fusions in Cancer.
  • SKY/M-FISH &CGH, A public platform for investigators to share and compare their molecular cytogenetic data.
  • TICdb, A database of Translocation breakpoints In Cancer.
  • References

  • Kong F, Zhu J, Wu J, Peng J, Wang Y, Wang Q, Fu S, Yuan L and Li T: dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. [PubMed] [Full-text]
  • Case ID: 12289
    Disease: Hypoplastic Left Heart ( DOID: 9955 )
    Reference Information
    PubMed ID: 19471316
    Authors: Gill HK,Parsons SR,Spalluto C,Davies AF,Knorz VJ,Burlinson CE,Ng BL,Carter NP,Ogilvie CM,Wilson DI,Roberts RG
    Journal: European journal of human genetics : EJHG
    Related Event(s):
    Event ID: 10694
    Precision: C
    Chromosome Rearrangement Type: Inversion
    Chromosome: 1
    Karyotype: inv(1)(q41q41)
    Breakpoints Information:
    First Breakpoint:
    Location: q41
    Second Breakpoint:
    Location: q41
    Junction Sequence is Unavailable.
    Experimental Method: FISH, PCR
    Related Event(s):
    Event ID: 11444
    Precision: A
    Chromosome Rearrangement Type: Reciprocal Translocation
    Chromosome: 1, 3
    Karyotype: t(1;3)(q41;q27.2)
    Breakpoints Information:
    First Breakpoint:
    Location: q41
    Exact position: Chr1: 214715823
    This breakpoint occurs in an intergenic region
    Second Breakpoint:
    Location: q27.2
    Exact position: Chr1: 185320520
    This breakpoint occurs in an intergenic region
    Junction Sequence(5'):
    ACAACAGGTGTCTGTCATAATGACGCGGGGGGGCAGCCTCAGCCTCACAGGGCATTCTTGGGCAAGGGGAAGGCAGACCTGCATGGACAGTTACAGGCAGGCTGAGGCAGTAGAATTGCTTGAACCCGGAAGCAGAGGGTGCAGTGAGCTAAGATTACACCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCT
    Junction Sequence(3'):
    TGCAGCCTGGCCAACATGGCGAGAAATCCCGTTTCTACTAAAAATAGAAAAATTAGCTAGGTGTGGTGGCACACACCTGTAGTCCCTGCTACTTGGGAGGGGGACATGGGGGAGTGAAGCAGTGGCAGTTCCCAGGCAGCTGACAGGCCAGTGAGGGGGTGAGGTAGGTTAACCAGGACACAGGGCACAGTGAGGTCAAT
    The Junction Sequence is Inferred.
    Note: Green and Blue color indicate 5' and 3' sequence according to the breakpoint.
    Experimental Method: FISH, PCR, DNA sequencing